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Eduardo Sontag

University Distinguished Professor, Electrical and Computer Engineering
Interdisciplinary, Bioengineering
326 ISEC
360 Huntington Avenue
Boston, MA 02115


  • PhD, University of Florida, 1977

Research & Scholarship Interests

Feedback control theory, systems biology, cancer, and biomedicine

Honors & Awards

  • IEEE Control Systems Field Award
  • IFAC Fellow
  • AMS Fellow
  • SIAM Fellow
  • IEEE Fellow
  • Reid Prize in Applied Mathematics, SIAM

Selected Publications

  • E.D. Sontag, A Dynamical Model of Immune Responses to Antigen Presentation Predicts Different Regions of Tumor or Pathogen Elimination, Cell Systems, 4, 2017, 1-11
  • E.D. Sontag, Dynamic Compensation, Parameter Identifiability, and Equivariances, PLoS Computational Biology, 13, 2017, 1005447
  • S. Barish, M.F. Ochs, E.D. Sontag, J.L. Gevertz, Evaluating Optimal Therapy Robustness by Virtual Expansion of a Sample Population, with a Case Study in Cancer Immunotherapy, Proceedings of the National Academy of Sciences, 114, 2017, 6277-6286
  • F. Menolascina, R. Rusconi, V.I. Fernandez, S.P. Smriga, Z. Aminzare, E.D. Sontag, R. Stocker, Logarithmic Sensing in Bacillus Subtilis Aerotaxis, Nature Systems Biology and Applications, 3, 2017, 16036
  • J. K. Kim, E.D. Sontag, Reduction of Multiscale Stochastic Biochemical Reaction Networks Using Exact Moment Derivation, PLoS Computational Biology, 13(6)m, 2017, 1005571
  • E.V. Nikolaev, E.D. Sontag, Quorum-Sensing Synchronization of Synthetic Toggle Switches: A Design Based on Monotone Dynamical Systems Theory, PLoS Computational Biology, 12, 2016, e1004881

Related News

March 28, 2018

ECE Distinguished Professor Eduardo Sontag developed a new technique that would give researchers the ability to control the behavior of engineered cells.

January 8, 2018

Eduardo Sontag joins the Electrical and Computer Engineering department in January 2018 as a University Distinguished Professor with a joint appointment in Bioengineering.