ECE Associate Professor Charles DiMarzio awarded a patent for “Deep tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light”.
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- PhD, Northeastern University, 1996
- J.L. Hollmann, R. Horstmeyer, C. Yang, C.A DiMarzio, Diffusion Model for Ultrasound-Modulated Light, Journal of Biomedical Optics, 19(3), 2014, 035005
- J.L. Hollmann, R.Horstmeyer, C. Yang, C.A. DiMarzio, Analysis and Modeling of an Ultrasound-Modulated Guide Star to Increase the Depth of Focusing in a Turbid Medium, Journal of Biomedical Optics, 18(2), 2013, 025004
- Z. Lai, J. Kerimo, Y. Mega, C.A. DiMarzio, Stepwise Multiphoton Activation Fluorescence Reveals a New Method of Melanin Detection, Journal of Biomedical Optics,18(6), 2013, 061225
- Z.R. Hoffman, C. DiMarzio, Structured Illumination Microscopy Using Random Intensity Incoherent Reflectance, Journal of Biomedical Optics, 2013
Prof. DiMarzio holds a BS in Engineering Physics (University of Maine), MS in Physics (WPI), and Ph.D. in Electrical and Computer Engineering (Northeastern University). Prior to coming to Northeastern, he was an engineer at Raytheon Company, working in coherent CO2 laser radar for remote sensing of the atmosphere and for other applications. At Northeastern, he continued laser radar activities, developed magnetic-field sensors based on the magneto-optical Kerr effect, and developed new optical techniques for landmine detection. More recently, his research has moved toward applications in medicine and biology. He invented optical quadrature microscopy for imaging phase objects, which has been used in research on embryo development. He also led the development of the Keck 3-D fusion microscope which combines optical quadrature with confocal and multi-photon microscopy for many applications in medicine and biology. He also pioneered novel techniques for medical imaging with ultrasound-modulated light.
He teaches graduate courses in optics, and a variety of undergraduate courses including engineering design, electronics and subsurface sensing & imaging. Prof. DiMarzio's Optical Science Laboratory enjoys collaborations with CenSSIS, the Center for Subsurface Sensing and Imaging Systems, with Prof. Carol Warner's biology laboratory at Northeastern, and with the dermatology department at Memorial Sloan Kettering Cancer Center.
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Despite the rapid progress in biomedical optics in the past decade, a need for ever-greater speed, resolution, and depth of imaging persists. For example, tissue sectioning with confocal reflectance...
ECE Associate Professor Charles DiMarzio was awarded a $300K NSF grant for "Coded-illumination Fourier Ptychography for High-content Multimodal Imaging".
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