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Prof. DiMarzio holds a BS in Engineering Physics (University of Maine), MS in Physics (WPI), and Ph.D. in Electrical and Computer Engineering (Northeastern University). Prior to coming to Northeastern, he was an engineer at Raytheon Company, working in coherent CO2 laser radar for remote sensing of the atmosphere and for other applications. At Northeastern, he continued laser radar activities, developed magnetic-field sensors based on the magneto-optical Kerr effect, and developed new optical techniques for landmine detection. More recently, his research has moved toward applications in medicine and biology. He invented optical quadrature microscopy for imaging phase objects, which has been used in research on embryo development. He also led the development of the Keck 3-D fusion microscope which combines optical quadrature with confocal and multi-photon microscopy for many applications in medicine and biology. He also pioneered novel techniques for medical imaging with ultrasound-modulated light.

He teaches graduate courses in optics, and a variety of undergraduate courses including engineering design, electronics and subsurface sensing & imaging. Prof. DiMarzio's Optical Science Laboratory enjoys collaborations with CenSSIS, the Center for Subsurface Sensing and Imaging Systems, with Prof. Carol Warner's biology laboratory at Northeastern, and with the dermatology department at Memorial Sloan Kettering Cancer Center.


  • PhD, Northeastern University, 1996

Research & Scholarship Interests

Optics, microscopy, coherent detection, interaction of light and sound waves, hyperspectral imaging, diffusive optical tomography and ultrasound, landmine detection, magneto-optic sensors, and multi-model imaging. Activities include computer modeling, designing, building, and testing of hardware, and processing the resulting data
Affiliated With

Department Research Areas

College Research Initiatives

Selected Publications

  • A.E. Draghici, D. Potart, J.L. Hollmann, V. Pera, Q. Fang, C.A. DiMarzio J.A. Taylor, M.J. Niedre, S.J. Shefelbine, Near Infrared Spectroscopy for Measuring Changes in Bone Hemoglobin Content after Exercise in Individuals with Spinal Cord Injury, Journal of Orthopaedic Research, 2017
  • Z.R. Hoffman, C.A. DiMarzio, Single-Image Structured Illumination Using Hilbert Transform Demodulation, Journal of Biomedical Optics, 22(5), 2017, 056011–056011
  • Z. R. Hoffman and C. A. DiMarzio, Super-Resolution Structured Illumination in Optically Thick Specimens Without Fluorescent Tagging, Journal of Biomedical Optics, 22(11), 2017, 1–11
  • A. Vakili, J.L. Hollmann, R.G. Holt, C.A. DiMarzio, Enhanced Tagging of Light Utilizing Acoustic Radiation Force with Speckle Pattern Analysis, Journal of Biomedical optics, 22(10), 2017, 106004
  • J.L. Hollmann, R. Horstmeyer, C. Yang, C.A DiMarzio, Diffusion Model for Ultrasound-Modulated Light, Journal of Biomedical Optics, 19(3), 2014, 035005
See Google Scholar Profile for all publications »

Related News

August 7, 2018

ECE Associate Professor Charles DiMarzio's group is collaborating with colleagues at Draper Laboratories on the development of an all-weather Lidar.

April 28, 2016

ECE Associate Professor Charles DiMarzio awarded a patent for “Deep tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light”.

January 25, 2016

Despite the rapid progress in biomedical optics in the past decade, a need for ever-greater speed, resolution, and depth of imaging persists. For example, tissue sectioning with confocal reflectance...

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