Present imaging techniques used in in vitro fertilization (IVF) clinics are unable to produce accurate cell counts in developing embryos past the eight cell stage. We have developed a method that has produced accurate cell counts in live mouse embryos ranging from 8 to 26 cells by combining Differential Interference Contrast (DIC) and Optical Quadrature Microscopy (OQM). This research deals with calculating the number of cells, dry mass, fragmentation and others embryo properties.
This research project is part of the work at the Optical Science Laboratory of Chuck DiMarzio in the Department of Electrical and Computer Engineering at Northeastern University. For other projects see Optical Science Lab Research Page.
Last update 4 Dec 2009