An innovative confocal reflectance microscope (CRM) with the ability of imaging skin in vivo has been developed. The confocal microscope presented employs a design that allows real time high resolution imaging of patients and facilitates more rapid detection of certain skin cancers. The design of this new microscope is based on an articulated arm which holds an objective lens and optical system to properly image the sample. Confocal microscopy is used experimentally to look at ex vivo samples from Mohs surgery, some imaging have been done in vivo with confocal microscopes, but the size and physical configuration of the microscope make it difficult for physicians to image patients in real time at any location on the patient.s body. Most skin cancers occur of the face/neck area, making it difficult to position the patient on a fixed confocal microscope. The confocal microscope presented is suitable for any clinical imaging applications requiring this kind of flexibility.
Optical Science Laboratory
This research project is part of the work at the Optical Science Laboratoty . of Chuck DiMarzio in the Department of Electrical and Computer Engineering at Northeastern University. For other projects see Optical Science Lab Research Page.