Refractive Errors and Corrections for OCT Images in an Inflated Lung Phantom

Research Overview

This research is in collaboration with Mechanical engineering department at Northeastern university on lung imaging utilizing OCT. We developed an inflated lung phantom, Bragg Nye bubble raft which is a hexagonal crystalline arrangement of sub-u m diameter bubbles that previously used in experimental atomic simulations, to understand, correct and validate refractive effects & artifacts of lung imaging under OCT by developing an experimental setup to provide ground truth along with developing a ray tracing algorithm to make the corrections.  We developed multi-angle tomography technique under OCT utilizing image registration to increase depth of imaging and signal-to-noise ratio in lung imaging.

Optical Science Laboratory

This research project is part of the work at the Optical Science Laboratory of Chuck DiMarzio in the Department of Electrical and Computer Engineering at Northeastern University. For other projects see Optical Science Lab Research Page.

  • Ali Golabchi, J. Faust, F. N. Golabchi, D. H. Brooks, A. Gouldstone and C. A. DiMarzio. "Refractive errors and corrections for OCT images in an inflated lung phantom." Biomedical Optic Express, 3, (5) 1101-1109 (2012).
  • Ali Golabchi, A. Gouldstone, and C. A. DiMarzio. "Multi Angle View of Lung Using Optical Coherence Tomography (OCT)." Proc. of SPIE, 8227, 82270X1-6 (2012)
  • Fatemeh N. Golabchi, Ali Golabchi, D. H. Brooks, A. Gouldstone and C. A. DiMarzio."Modeling the eff ect of refraction on OCT imaging of lung tissue: a ray-tracing approach"Proc. of SPIE, 8227,
    82271R1-5 (2012)

    Last update 11 July 2012