Axotomy and Calcium Imaging on C. elegans

Research Overview

Axotomy is the cutting of an axon to study neuronal physiology and to better understand nervous system diseases. Calcium imaging, as one of the aims of doing axotomy in living animals, is a technique which shows the calcium concentration of the cell or tissue. The amplitude of axonal calcium correlates with the regeneration of injured axons. Caenohabditis elegans is a good sample to do axotomy and calcium imaging on because of its simple structures as an invertebrate and because of its availability of extensive genetic tools.

Optical Science Laboratory

This research project is part of the work at the Optical Science Laboratory of Chuck DiMarzio in the Department of Electrical and Computer Engineering at Northeastern University. For other projects see Optical Science Lab Research Page.

Last update 30 July 2012