Speaker: Dr. Mehdi Moghari, Boston Children's Hospital
Host: ECE Professor Dana Brooks
Cardiovascular magnetic resonance (CMR) imaging is an emerging modality that provides unique measurements and observations to cardiologists and cardiac surgeons. Although echocardiography, X-ray angiography, and multi-detector computed tomography are conventionally used in clinical practice, CMR is a noninvasive and complementary technique that offers gold standard measurements for the assessment of cardiac function and pre-procedural planning of patients with heart disease.
To further improve the prognostic and diagnostic value of CMR, images with a high spatiotemporal resolution is required. However, the acquisition of images with high spatiotemporal resolution is challenging in CMR due to the long scan-time that necessitates free-breathing acquisitions with a respiratory motion compensation algorithm. In this talk, the conventional respiratory motion compensation algorithm in CMR is introduced. Then, a novel respiratory motion compensation algorithm based on Compressed Sensing is presented to reduce scan-time and improve the spatiotemporal resolution images. The acquired CMR images are then semi-automatically segmented to isolate the blood-pool and cardiac muscle from the background and surrounding tissues. The segmented cardiac muscle is used to generate virtual and physical heart models of patients with cardiac disease for cardiac surgery. The created virtual and physical models of the heart are static and visualize cardiac structure in only one cardiac phase. Our future goal would be creating a beating virtual heart model showing cardiac structure through the cardiac cycle and fusing the blood circulation on the beating virtual heart model to simulate cardiac surgery and optimize pre-procedural planning.
Mehdi Hedjazi Moghari received his B.Sc. and M.Sc. degrees in Electrical Engineering from Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran in 1999 and 2002. He received a Ph.D. degree in Electrical and Computer Engineering at Queen’s University, Kingston, Ontario, Canada, in 2008. During 2009 and 2012, he continued his research on CMRI, as a postdoctoral research fellow, at Beth Israel Deaconess Medical Center, Boston, MA, USA. He is now a research associate at the Department of Cardiology at Boston Children’s Hospital and an Instructor in Pediatrics at Harvard Medical School. His research interests on CMRI include pulse sequence design, motion compensation, image registration, and reconstruction.